Fresh deployment of ZENworks Service Desk 25.1 is not supported. However, you can deploy ZENworks Service Desk 24.1, and then update to ZENworks Service Desk 25.1. ZENworks Service Desk 25.1 is available only through Online channel (Online Update channel).
Fresh Appliance Deployment
To deploy ZENworks Service Desk 24.1, see the Appliance Deployment section in the Service Desk Appliance Deployment and Administration Reference.
Update to ZENworks Service Desk 25.1
To update to ZENworks Service Desk 25.1, see Migrating the Appliance.
Updating ZENworks Service Desk older than ZENworks 24.1
If you are using any version older than ZENworks Service Desk 24.1, then refer to ZENworks Service Desk 24.1 Appliance Deployment and Administration Reference.